What Do We Know About How Generative AI is Being Used for Patient-Centered Communication? A Scoping Review

This paper offers a scoping review of extant research examining how generative artificial intelligence (AI) is being designed, tested, and used to facilitate patient-centered communication. Using the Joanna Briggs Institute methodology and PRISMA-ScR guidelines, we analyzed 221 publications from 2020 to 2025 across eight databases. Five themes emerged to depict previous research studying how AI healthcare applications have furthered patient-centered communication, including (1) the use of conversational agents and social robots to increase patient engagement, (2) using NLP to examine patient information texts to glean insights that can enhance patient communication, (3) employing LLMs to generate patient-friendly clinical reports and answer patient-specific medical questions, (4) integrating AI into digital health platforms to enhance patient reporting and self-management, and (5) integrating AI into decision support tools that facilitate shared decision-making and automate routine tasks so that physicians can spend more time communicating with patients. New AI tools show promise in increasing efficiency, care personalization, and emotional support, but research gaps remain. Specifically, a future agenda calls for scholars to further investigate how AI can be designed for equitable patient communication, how AI can enhance communication during health transitions, how AI tools can better involve family and caregivers in patient-centered communication, and longitudinal studies that evidence AI's impact on real-world outcomes over time, among others.