NIR-II photothermal CSGGT hydrogel for antibacterial therapy and accelerated healing of infected wounds

-infected murine full-thickness wound model, CSGGT + NIR achieved near-complete closure by day 12, with robust re-epithelialization, regenerated skin appendages, dense collagen deposition, and reduced inflammatory infiltration, significantly outperforming all controls. No systemic toxicity was observed. This work presents a combined therapeutic platform that merges immediate photothermal antibacterial action with sustained pro-healing microenvironment support, offering a promising non-antibiotic solution for infected wound management.