Neat metal-organic framework CIM-80(Al) onto silver braid supports to expand solid-phase microextraction applicability towards fast analysis

Metal-organic frameworks (MOFs) constitute excellent extractant phases due to their high surface area, tunable porosity, and adequate chemical stability. This study presents a novel SPME configuration involving MOFs, formed by the crystalline coating directly grown onto a silver braid support rather than other metallic supports with lower chemical tunabilty. The unique braided disposition of the support provides increased surface area for MOF immobilization, thus promoting higher coating surface and improved extraction efficiency. The method was systematically optimized (with particular attention to extraction time and temperature) and evaluated for the determination of two families of organic pollutants, including aliphatic (C 8 to C 31 ) and sixteen polycyclic aromatic hydrocarbons. The adsorption partitioning of the analytes to the SPME coatings was confirmed through studies on the extraction mechanism, and a comparison was commercial fibers was also carried out. This work highlights the advantages of MOF-braided SPME fibers for high-throughput sample preparation, offering a versatile platform for rapid and sensitive untargeted analysis in complex matrices, while offering complementary results to commercial fibers. Thus, the MOF-braided fiber, using the green MOF CIM-80( Al ), was responsible of 60% and 45% of the total number of analytes identified in breath and exhaust car pipe, respectively, with only 2 min of extraction time (as SPME fiber exposure to the samples). The relative standard deviation (RSD) of the batch-to-batch reproducibility of the SPME fibers, tested with real samples in the entire HS-SPME-GC–MS, presented an average RSD of 17.7% ( n = 5 different batches) with an average lifetime of 40 uses. • New braid MOF-based SPME fiber with silver support for better attachment. • Deep study of performance in HS-SPME-GC–MS while comparing with PDMS. • Insights on the MOF adsorption mechanism for hydrocarbons. • Fast biological and environmental analysis of breath and exhaust pipe samples. • Simultaneous target and non-target analytical approach with these MOF fibers.