三氟甲基
环加成
化学
氟
区域选择性
镍
双键
药物化学
键裂
劈理(地质)
有机化学
催化作用
材料科学
断裂(地质)
复合材料
烷基
作者
Tomohiro Ichitsuka,Takeshi Fujita,Tomohiro Arita,Junji Ichikawa
标识
DOI:10.1002/anie.201402695
摘要
Abstract The nickel‐mediated [3+2] cycloaddition of 2‐trifluoromethyl‐1‐alkenes with alkynes afforded fluorine‐containing multi‐substituted cyclopentadienes in a regioselective manner. This reaction involves the consecutive two CF bond cleavage of a trifluoromethyl or a pentafluoroethyl group through β‐fluorine elimination.
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