胶粘剂
体外
粘液
体内
药物输送
化学
药品
材料科学
高分子化学
生物医学工程
药理学
纳米技术
医学
生物化学
生物
生物技术
生态学
图层(电子)
作者
John D. Smart,I.W. Kellaway,H. E. C. Worthington
标识
DOI:10.1111/j.2042-7158.1984.tb04377.x
摘要
An in-vitro test system was developed to investigate the adhesiveness of various materials to mucus. The results obtained showed good agreement with the findings of previous in-vivo evaluations of mucosa-adhesives. Further investigations found that these materials become adhesive on hydration. Chain length, and the presence of ionizable groups in the molecule, were found to be determinate factors. The physical nature of the gel, and the location at which the mucoadhesive materials hydrated, were of less importance.
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