医学
英国前瞻性糖尿病研究
糖化血红素
二甲双胍
2型糖尿病
糖尿病
内科学
心肌梗塞
磺酰脲
临床终点
2型糖尿病
随机对照试验
胰岛素
内分泌学
作者
Rury R. Holman,Sanjoy K. Paul,M. Angelyn Bethel,David R. Matthews,H. A. W. Neil
标识
DOI:10.1056/nejmoa0806470
摘要
Despite an early loss of glycemic differences, a continued reduction in microvascular risk and emergent risk reductions for myocardial infarction and death from any cause were observed during 10 years of post-trial follow-up. A continued benefit after metformin therapy was evident among overweight patients. (UKPDS 80; Current Controlled Trials number, ISRCTN75451837.)
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