Study of correlation between cytomegalovirus infection and the changes of intracellular [Ca~(2+)] concentration

Human cytornegalovirus (HCMV) infection is very common in human being, but the mechanisms of causing damage is understood poorly. Calcium is the most important component in the process of intracellular signal transduction. Also, calcium plays a important role in a series of intracellular reaction of physiology and biochemistry and the occurrence and development of diseases. HCMV infection can significantly affect intracellular [Ca2+] concentration of infected cells, which are not only favor to the replication and maturation of intracellular viruses, but the pathogenicity.