To analyse the clinical course of 412 patients with liver dysfunction in measles.The result showed an elevation of aspartate aminotrasferase(AST), alanine aminotransferase(ALT),lactate dehydrogenase(ADH) and bile acids(BA). Clinical course of liver dysfunction was 89.8 percent of all measles courses. Liver dysfunction rate of adults had no significant difference from that of child. The analysis showed that liver was one of important damaged Organs. Liver function examination was very necessary in measles. treatment of measles in liver dysfunction ought to be according to return of liver function.