Application of Angio-Seal vascular closure device following coronary angiograph and percutaneous coronary intervention by way of femoral artery

Objective To evaluate the safety and efficacy of the application of Angio-Seal vascular closure device(VCD) following coronary angiograph(CAG) and percutaneous coronary intervention(PCI) by way of femoral artery.Methods According to the methods used for hemostasis following CAG and PCI,582 patients were divided into two groups(Group A n=220,Group B n=362).Patients in Group A received VCD for hemostasis, while patients in group B received manual compression(MC).The successful rate of hemostasis,the incidence of hemorrhagic complications and vasovagal reflex in the two groups were compared.Results There were no significant differences in the successful rate of hemostasis and the incidence of hemorrhagic complications,but there was significant difference in vasovagal reflex between the two groups.Conclusions The VCD did not superior to MC in the the successful rate of hemostasis and the incidence of hemorrhagic complications,but its price is high.Thus, VCD could not be a routine method for hemostasis after CAG and PCI by way of femoral artery.