Efficient A·T to G·C base conversions in dicots using adenine base editors expressed under the tomato EF1α promoter

Plant Biotechnology JournalAccepted Articles BRIEF COMMUNICATIONSOpen Access Efficient A·T to G·C Base Conversions in Dicots Using Adenine Base Editors Expressed under the Tomato EF1α Promoter Qingfeng Niu, Qingfeng Niu Shanghai Center for Plant Stress Biology, and National Key Laboratory of Plant Molecular Genetics, Center of Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032 ChinaThese authors contributed equally to this workSearch for more papers by this authorSiqun Wu, Siqun Wu Shanghai Center for Plant Stress Biology, and National Key Laboratory of Plant Molecular Genetics, Center of Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032 China University of Chinese Academy of Sciences, Beijing, 100049 ChinaThese authors contributed equally to this workSearch for more papers by this authorHongtao Xie, Hongtao Xie Shandong Shunfeng Biotechnology Co, Ltd, Jinan, 250000 ChinaThese authors contributed equally to this workSearch for more papers by this authorQi Wu, Qi Wu Shanghai Center for Plant Stress Biology, and National Key Laboratory of Plant Molecular Genetics, Center of Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032 China University of Chinese Academy of Sciences, Beijing, 100049 ChinaSearch for more papers by this authorPing Liu, Ping Liu Shanghai Center for Plant Stress Biology, and National Key Laboratory of Plant Molecular Genetics, Center of Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032 ChinaSearch for more papers by this authorYaping Xu, Yaping Xu Shanghai Center for Plant Stress Biology, and National Key Laboratory of Plant Molecular Genetics, Center of Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032 China University of Chinese Academy of Sciences, Beijing, 100049 ChinaSearch for more papers by this authorZhaobo Lang, Corresponding Author Zhaobo Lang zblang@cemps.ac.cn orcid.org/0000-0002-5551-0126 Shanghai Center for Plant Stress Biology, and National Key Laboratory of Plant Molecular Genetics, Center of Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032 China Corresponding author Zhaobo Lang (zblang@cemps.ac.cn)Search for more papers by this author Qingfeng Niu, Qingfeng Niu Shanghai Center for Plant Stress Biology, and National Key Laboratory of Plant Molecular Genetics, Center of Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032 ChinaThese authors contributed equally to this workSearch for more papers by this authorSiqun Wu, Siqun Wu Shanghai Center for Plant Stress Biology, and National Key Laboratory of Plant Molecular Genetics, Center of Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032 China University of Chinese Academy of Sciences, Beijing, 100049 ChinaThese authors contributed equally to this workSearch for more papers by this authorHongtao Xie, Hongtao Xie Shandong Shunfeng Biotechnology Co, Ltd, Jinan, 250000 ChinaThese authors contributed equally to this workSearch for more papers by this authorQi Wu, Qi Wu Shanghai Center for Plant Stress Biology, and National Key Laboratory of Plant Molecular Genetics, Center of Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032 China University of Chinese Academy of Sciences, Beijing, 100049 ChinaSearch for more papers by this authorPing Liu, Ping Liu Shanghai Center for Plant Stress Biology, and National Key Laboratory of Plant Molecular Genetics, Center of Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032 ChinaSearch for more papers by this authorYaping Xu, Yaping Xu Shanghai Center for Plant Stress Biology, and National Key Laboratory of Plant Molecular Genetics, Center of Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032 China University of Chinese Academy of Sciences, Beijing, 100049 ChinaSearch for more papers by this authorZhaobo Lang, Corresponding Author Zhaobo Lang zblang@cemps.ac.cn orcid.org/0000-0002-5551-0126 Shanghai Center for Plant Stress Biology, and National Key Laboratory of Plant Molecular Genetics, Center of Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032 China Corresponding author Zhaobo Lang (zblang@cemps.ac.cn)Search for more papers by this author First published: 25 October 2021 https://doi.org/10.1111/pbi.13736 This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi:10.1111/pbi.13736 AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas systems have revolutionized plant breeding. Different Cas enzymes have been widely used to introduce deletions or insertions into plant genomes. However, many important agronomical traits in plants are associated with single nucleotide polymorphisms. For example, the Lin5 SNP causes an Asn366 to Asp change, resulting in a higher sugar content in tomato fruits (Tieman et al., 2017). Thus, it is important to develop tools to efficiently introduce precise base changes in crops. Accepted ArticlesAccepted, unedited articles published online and citable. The final edited and typeset version of record will appear in the future. RelatedInformation