Abstract This chapter contains a case study to present the valuable skills, attitudes, and knowledge needed to diagnose and manage anorexia-cachexia. It addresses several questions such as: What are the definitions of anorexia and cachexia? What are the clinical characteristics of patients with anorexia-cachexia syndrome? Are some cancers more likely than others to cause cachexia? How does a chronic inflammatory state cause cachexia? What is the framework for your anorexia-cachexia therapeutic platform?