Intense 68Ga-PSMA-11 Uptake of Perihilar Cholangiocarcinoma

An immunohistochemical study demonstrates that most of the cholangiocarcinomas have PSMA expression in the tumor neovasculature. PSMA PET findings of cholangiocarcinomas are rarely reported. We describe 68 Ga-PSMA-11 PET/CT and delayed abdominal 68 Ga-PSMA-11 PET/MRI findings in a case of mass-forming type of perihilar cholangiocarcinoma. The tumor showed intense PSMA uptake with SUV max of 10.8 on 68 Ga-PSMA-11 PET/CT and SUV max of 7.8 on delayed 68 Ga-PSMA-11 PET/MRI.