医学
孕酮受体
接收机工作特性
雌激素受体
入射(几何)
内科学
雌激素
受体
内分泌学
子宫内膜息肉
妇科
子宫内膜
癌症
乳腺癌
物理
光学
作者
Cardex Yan,Chao Xing,Tao Wei,Hui Zhou,Hua Wang,Tao Liu,Jiefang Gao
出处
期刊:Biomarkers in Medicine
[Future Medicine]
日期:2023-11-01
卷期号:17 (21): 881-887
标识
DOI:10.2217/bmm-2023-0411
摘要
Aim: We studied the association of estrogen receptor (ER) and progesterone receptor (PR) with endometrial polyp (EP) formation. Methods: A total of 129 EP patients and an equal number of disease-free women were evaluated for ER and PR expression in endometrial tissues. Correlation with EP incidence was analyzed, as well as diagnostic value via receiver operating characteristic curve. Results: ER expression was higher and PR was lower in patients than in controls (p < 0.01). ER levels positively correlated with EP incidence, and PR negatively (p < 0.01). Receiver operating characteristic curves gave ER an area under the curve of 0.6168 (95% CI: 0.5479-0.6856; p < 0.0001) and PR 0.739 (95% CI: 0.6776-0.8003; p < 0.0001). Conclusion: Imbalance in ER and PR expression associates with EPs formation, offering clinical insights into EP pathology.
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