冷漠
失智症
去抑制
萎缩
痴呆
抗精神病药
精神病
心理学
医学
精神科
儿科
精神分裂症(面向对象编程)
疾病
内科学
认知
作者
Tania C Ghazarian,Matthew G. H. Hall,Leslie A Horton,Bruce L. Miller,Robert T. Rubín
出处
期刊:Neurocase
[Informa]
日期:2023-01-02
卷期号:29 (1): 6-13
标识
DOI:10.1080/13554794.2023.2191858
摘要
A 23-year-old man presented with behavioral disinhibition, stereotypies, motor apathy, flattened affect, and inappropriate laughter. CT demonstrated generalized cerebral atrophy. He was admitted with a diagnosis of unspecified psychosis and discharged on antipsychotic medication. He was readmitted 3 months later, was diagnosed with schizophrenia, and antipsychotic medication was continued. Owing to symptom progression and aggressive behavior, he was readmitted 2 months later. CT again demonstrated moderate central and cortical cerebral atrophy. MRI showed severe, stable atrophy with frontotemporal predominance, and he was diagnosed with probable behavioral variant frontotemporal dementia (bvFTD). Over the next year he rapidly deteriorated, with loss of cognitive abilities. Genetic testing revealed several variants, none of which are clearly disease-causing.
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