Aesthetic (cosmetic) devices are used to treat a wide variety of issues associated with a person’s looks and aesthetic appearance, for example skin laxity, excessive fat, cellulite, scars, stretchmarks, unwanted tattoos, pigmented lesions, wrinkles, excess hair, age spots, spider veins, and skin discoloration. They may be regulated by the FDA depending upon their intended use and whether they impact the structure or function of the body. It is important for patients to discuss the benefits and risks of these devices with their healthcare providers to make an informed decision on whether to use these devices. This chapter will provide detailed information on aesthetic devices and their applications.