视网膜
生物碱
炎症
化学
缺氧(环境)
血管生成
视网膜色素上皮
颜料
药理学
生物化学
医学
生物
癌症研究
内科学
立体化学
有机化学
氧气
作者
Ting-En Chen,Jung Lo,Shu‐Pin Huang,Kun‐Che Chang,Po‐Len Liu,Hsin‐En Wu,Yuan-Ru Chen,Yo-Chen Chang,Ching‐Chih Liu,Po‐Yen Lee,Yu‐Hung Lai,Pei‐Chang Wu,Shu‐Chi Wang,Chia‐Yang Li
标识
DOI:10.1016/j.ejphar.2024.176883
摘要
Glaucine is an aporphine alkaloid with anti-inflammatory, bronchodilator and anti-cancer activities. However, the effects of glaucine in the regulation of age-related macular degeneration (AMD) remain unclear. Herein, we aimed to investigate the anti-angiogenetic and anti-inflammatory effects of glaucine in ARPE-19 cells. ARPE-19 cells were treated with N-(methoxyoxoacetyl)-glycine, methyl ester (DMOG) and cobalt chloride (CoCl
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