孟德尔随机化
医学
腔隙性中风
冲程(发动机)
代谢组
内科学
代谢物
生物信息学
生物化学
基因
生物
基因型
缺血性中风
缺血
工程类
机械工程
遗传变异
作者
Mengnan Guo,Xiaoyan Hao,Jie Tian,Yunchao Wang,Jiadi Li,Yu Fan,Jingjing Shi,Dongrui Ma,Shuangjie Li,Chunyan Zuo,Yuanyuan Liang,Mengjie Li,Si Shen,Fen Liu,Dabao Yao,Yuming Xu,Changhe Shi
标识
DOI:10.1177/17474930221140792
摘要
We identified eight risk and seven protective human serum metabolites associated with lacunar stroke. Isobutyrylcarnitine was positively associated with an increased risk of lacunar stroke. In addition, 3-methyl-2-oxovalerate and aspartate may be involved in the disease pathogenesis through metabolic pathways.
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