索拉非尼
医学
肝细胞癌
内科学
血管内皮生长因子
癌
血管内皮生长因子受体
肿瘤科
癌症研究
作者
Josep M. Llovet,Sergio Ricci,Vincenzo Mazzaferro,Philip Hilgard,Edward Gane,Jean Frédéric Blanc,André Cosme de Oliveira,Armando Santoro,Jean‐Luc Raoul,Alejandro Forner,Myron Schwartz,Camillo Porta,Stefan Zeuzem,Luigi Bolondi,Tim F. Greten,Peter R. Galle,Jean François Seitz,Ivan Borbath,Dieter Häussinger,Tom Giannaris
标识
DOI：10.1056/nejmoa0708857
摘要
No effective systemic therapy exists for patients with advanced hepatocellular carcinoma. A preliminary study suggested that sorafenib, an oral multikinase inhibitor of the vascular endothelial growth factor receptor, the platelet-derived growth factor receptor, and Raf may be effective in hepatocellular carcinoma.
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