Mendelian randomization highlights causal association between genetically increased C‐reactive protein levels and reduced Alzheimer's disease risk

Alzheimer's & DementiaEarly View LETTER Mendelian randomization highlights causal association between genetically increased C-reactive protein levels and reduced Alzheimer's disease risk This article relates to: Reply to “Mendelian randomization highlights causal association between genetically increased C-reactive protein levels and reduced Alzheimer's disease risk” Jiao Luo, Jesper Qvist Thomassen, Sharif H. Hegazy, Ida Juul Rasmussen, Børge G. Nordestgaard, Anne Tybjærg-Hansen, Ruth Frikke-Schmidt, Alzheimer's & Dementia First Published online: May 22, 2022 Yang Hu, Yang Hu School of Life Science and Technology, Harbin Institute of Technology, Harbin, ChinaSearch for more papers by this authorYan Zhang, Yan Zhang Department of Pathology, The Affiliated Hospital of Weifang Medical University, Weifang, ChinaSearch for more papers by this authorHaihua Zhang, Haihua Zhang Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, ChinaSearch for more papers by this authorShan Gao, Shan Gao Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, ChinaSearch for more papers by this authorLongcai Wang, Longcai Wang Department of Anesthesiology, The Affiliated Hospital of Weifang Medical University, Weifang, ChinaSearch for more papers by this authorTao Wang, Tao Wang Chinese Institute for Brain Research, Beijing, ChinaSearch for more papers by this authorZhifa Han, Zhifa Han State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, ChinaSearch for more papers by this authorInternational Genomics of Alzheimer's Project (IGAP), International Genomics of Alzheimer's Project (IGAP)Search for more papers by this authorGuiyou Liu, Corresponding Author Guiyou Liu liuguiyou1981@163.com orcid.org/0000-0002-1126-2888 Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China Chinese Institute for Brain Research, Beijing, China Key Laboratory of Cerebral Microcirculation in Universities of Shandong, Department of Neurology, Second Affiliated Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, China Beijing Key Laboratory of Hypoxia Translational Medicine, National Engineering Laboratory of Internet Medical Diagnosis and Treatment Technology, Xuanwu Hospital, Capital Medical University, Beijing, China Correspondence Guiyou Liu, Beijing Institute for Brain Disorders, Capital Medical University, Room 725, Morphology Building, No. 10, Xitoutiao, You'an Men Wai, Fengtai District, Beijing 100069, China. E-mail: liuguiyou1981@163.comSearch for more papers by this author Yang Hu, Yang Hu School of Life Science and Technology, Harbin Institute of Technology, Harbin, ChinaSearch for more papers by this authorYan Zhang, Yan Zhang Department of Pathology, The Affiliated Hospital of Weifang Medical University, Weifang, ChinaSearch for more papers by this authorHaihua Zhang, Haihua Zhang Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, ChinaSearch for more papers by this authorShan Gao, Shan Gao Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, ChinaSearch for more papers by this authorLongcai Wang, Longcai Wang Department of Anesthesiology, The Affiliated Hospital of Weifang Medical University, Weifang, ChinaSearch for more papers by this authorTao Wang, Tao Wang Chinese Institute for Brain Research, Beijing, ChinaSearch for more papers by this authorZhifa Han, Zhifa Han State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, ChinaSearch for more papers by this authorInternational Genomics of Alzheimer's Project (IGAP), International Genomics of Alzheimer's Project (IGAP)Search for more papers by this authorGuiyou Liu, Corresponding Author Guiyou Liu liuguiyou1981@163.com orcid.org/0000-0002-1126-2888 Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China Chinese Institute for Brain Research, Beijing, China Key Laboratory of Cerebral Microcirculation in Universities of Shandong, Department of Neurology, Second Affiliated Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, China Beijing Key Laboratory of Hypoxia Translational Medicine, National Engineering Laboratory of Internet Medical Diagnosis and Treatment Technology, Xuanwu Hospital, Capital Medical University, Beijing, China Correspondence Guiyou Liu, Beijing Institute for Brain Disorders, Capital Medical University, Room 725, Morphology Building, No. 10, Xitoutiao, You'an Men Wai, Fengtai District, Beijing 100069, China. E-mail: liuguiyou1981@163.comSearch for more papers by this author First published: 22 May 2022 https://doi.org/10.1002/alz.12687Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Early ViewOnline Version of Record before inclusion in an issue RelatedInformation