粘蛋白
鼠李糖乳杆菌
微生物学
肠道菌群
生物
食品科学
益生菌
乳酸菌
化学
生物化学
细菌
遗传学
发酵
作者
Yu Gu,Xiali Qin,Guoqiong Zhou,Chen Wang,Chenlu Mu,Xiang Liu,Weilong Zhong,Xin Xu,Bangmao Wang,Kui Jiang,Jinghua Liu,Hailong Cao
出处
期刊:Food & Function
[Royal Society of Chemistry]
日期:2022-01-01
卷期号:13 (23): 12144-12155
被引量:52
摘要
XlVa in the LGGs group, which have been reported to be involved in regulating gut motility and the intestinal barrier, and alleviating bowel dysfunction. Interestingly, gut dysbiosis was present in the tegaserod group. It is noteworthy that the fecal microbiota transplanted from LGGs-treated mice significantly improved the gut dysmotility in a constipation mouse model. Our results suggested that LGGs could upregulate 5-HT4R to promote MUC2 production, as well as modulate the gut microbiota, thus improving the defecation function in mice. This finding might provide evidence for the application of diet supplementary LGG in relieving gastrointestinal motility disorders.
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