Synthesis of trifluoromethyl-functionalized benzo[ de ][1,8]naphthyridines via Rh( iii )-catalyzed two-fold C–H activation of benzamidine hydrochlorides and annulation with CF 3 -imidoyl sulfoxonium ylides

A Rh( iii )-catalyzed two-fold C–H activation of benzamidine hydrochlorides and cascade annulation with CF 3 -imidoyl sulfoxonium ylides (TFISYs) has been disclosed.