Semaglutide attenuates diabetic retinopathy progression via ameliorating retinal vasculopathy and oxidative stress in vivo and in vitro

Semaglutide slows the progression of diabetic retinopathy by improving retinal vascular lesions and reducing oxidative stress. Its mechanism of action may involve the reduction of inflammation and apoptosis. Its overall protective effect on retinal function and oxidative stress highlights its potential as a therapeutic drug for diabetic retinopathy. Further mechanisms and clinical studies are needed to validate these findings and assess the long-term effects.