Downregulation of SIRT6 and NMNAT2 is associated with proliferative diabetic retinopathy.

Purpose: in diabetic retinopathy (DR). Methods: 2 in proliferative DR (PDR) and the control subjects. Results: in the fibrovascular membranes of PDR patients. Conclusions: in PDR patients reveals a potential pathogenic association; more extended studies could verify them as potential therapeutic targets.