Current Perspective and Mechanistic Insights on α‐Hederin for the Prevention and Treatment of Several Noncommunicable Diseases

疾病 神经保护 癌症 医学 哮喘 神经科学 生物信息学 药理学 免疫学 生物 内科学
作者
Riham A. El‐Shiekh,Ahmed M. Atwa,Ali M. Elgindy,Kawther Magdy Ibrahim,Mohamed Magdy Senna,Nouran Ebid,Aya M. Mustafa
出处
期刊:Chemistry & Biodiversity [Wiley]
卷期号:22 (4): e202402289-e202402289 被引量:2
标识
DOI:10.1002/cbdv.202402289
摘要

ABSTRACT α‐Hederin, a naturally occurring compound found in various plant sources, has remarkable properties and therapeutic potential for human health. One notable attribute is its potent anti‐inflammatory activity, such as in arthritis, asthma, and inflammatory bowel disease. In addition, it exhibits notable antioxidant effects implicated in the development of chronic diseases, including cardiovascular disorders and certain types of cancer. According to research, it may limit the growth and proliferation of cancer cells, making it a possible candidate for future cancer treatments. Moreover, it is a promising neuroprotective agent and enhances cognitive function, suggesting its potential in the treatment of neurodegenerative illnesses like Alzheimer's and Parkinson's disease. The multifaceted benefits of α‐hederin make it an intriguing compound with significant therapeutic implications. As research progresses, exploring its mechanisms of action and clinical applications is warranted. Harnessing the potential of α‐hederin may pave the way for innovative treatment strategies and improved outcomes in the battle against various chronic diseases.

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