坏死性下垂
自噬
肺炎链球菌
肺炎
医学
微生物学
化学
生物
程序性细胞死亡
抗生素
内科学
细胞凋亡
生物化学
作者
Tangbin Tian,Zhigang Xue,Xiaozhou Sun,Lizhong Ding,Renshuang Zhao,Zhongtian Wang,Jiaqi Wu,Li Xiao,Yiquan Li,Liping Sun
出处
期刊:Phytomedicine
[Elsevier]
日期:2024-11-29
卷期号:136: 156280-156280
被引量:3
标识
DOI:10.1016/j.phymed.2024.156280
摘要
This study demonstrated that QFY can effectively alleviate S. pneumoniae pneumonia. The mechanism of action may be that QFY promotes complete autophagy by downregulating p62 expression, thereby alleviating necroptosis of S. pneumoniae-induced lung epithelial cells and reducing lung injury. It provides a scientific basis for clinical prevention and treatment of S. pneumoniae pneumonia.
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