The fermented kelp by Bacillus siamensis has antioxidant, skin-repairing and anti-wrinkle effects

In the present study, we explored the properties of Bacillus siamensis-fermented kelp as a raw material for the preparation of cosmetics. We found that the content of polysaccharide in the kelp fermentation broth was 343.90 ± 8.63 mg/g, the content of fucose was 127.55 ± 9.55 mg/g, and the content of alginic acid was 322.00 ± 14.14 mg/g. The scavenging rate of DPPH free radicals of the kelp fermentation broth was 95.08 ± 1.60 %, showing good antioxidant capacity. Moreover, high tyrosinase activity inhibition could suppress hyperpigmentation. Furthermore, morphological observation, CCK-8 assay, and would healing assay were used to test the anti-wrinkle and skin-repairing effects of the fermentation broth on skin cells. The results show that Bacillus siamensis fermentation broth of kelp at a dilution of 1:1000 could effectively promote the growth of skin cells HaCaT and HFF-1, showing good skin-repairing and anti-wrinkle effects. Collectively, the Bacillus siamensis fermentation broth of kelp could be used as a cosmetic raw material.