哮喘
医学
单克隆抗体
炎症
免疫学
临床试验
精密医学
单克隆
免疫系统
抗体
重症监护医学
内科学
病理
作者
Imran Howell,Aleksandra Howell,Ian D. Pavord
摘要
The field of asthma has undergone a dramatic change in recent years. Advances in our understanding of type 2 airway inflammation have driven the discovery of monoclonal antibodies targeting specific aspects of the immune pathway. In landmark trials, these drugs have shown efficacy in reducing asthma attacks and exposure to oral corticosteroids, important causes of morbidity in people with asthma. Our review explores the key features of type 2 inflammation in asthma and summarizes the clinical trial evidence of the novel monoclonal antibody treatments and future avenues for treatment.
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