混淆
因果关系(物理学)
孟德尔随机化
随机化
下巴
因果推理
工具变量
医学
孟德尔遗传
随机对照试验
生物
病理
遗传学
基因
基因型
数学
统计
遗传变异
物理
解剖
量子力学
出处
期刊:Chinese journal of ophthalmology
日期:2021-10-11
卷期号:57 (10): 791-795
标识
DOI:10.3760/cma.j.cn112142-20210302-00102
摘要
In recent years, the application of Mendelian randomization has become more and more widely in the world. By taking genes as instrumental variables, it can eliminate the interference of confounding factors and reverse causality in the system, and effectively judge the causal correlation between exposure factors and outcomes, which has a unique advantage for etiological exploration in the medical field. This article reviews the application of Mendelian randomization in ophthalmology and provides new ideas for the development of correlational and causal studies in Ophthalmology. (Chin J Ophthalmol, 2021, 57: 791-795).
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