Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTNucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)Ulrich Lächelt*†‡ and Ernst Wagner*†‡View Author Information† Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig Maximilians Universität, 81377 Munich, Germany‡ Nanosystems Initiative Munich (NIM), 80799 Munich, Germany*E-mail: [email protected]*E-mail: [email protected]Cite this: Chem. Rev. 2015, 115, 19, 11043–11078Publication Date (Web):April 15, 2015Publication History Received30 November 2014Published online15 April 2015Published inissue 14 October 2015https://pubs.acs.org/doi/10.1021/cr5006793https://doi.org/10.1021/cr5006793review-articleACS PublicationsCopyright © 2015 American Chemical SocietyRequest reuse permissionsArticle Views9095Altmetric-Citations486LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Gene delivery,Genetics,Nucleic acids,Polyethylenimine,Polymers Get e-Alerts