逐渐变细
信号(编程语言)
光纤
纤维
灵敏度(控制系统)
材料科学
光纤传感器
光学
再现性
生物传感器
多模光纤
化学
电子工程
计算机科学
物理
纳米技术
复合材料
程序设计语言
工程类
计算机图形学(图像)
色谱法
作者
George P. Anderson,Joel P. Golden,Frances S. Ligler
标识
DOI:10.1016/0956-5663(93)80012-e
摘要
One of the most critical features of an evanescent wave fiber optic biosensor is the design of the fiber probe's sensing region. The initial fibers tested exhibited poor sensitivity, primarily due to loss of fluorescent signal which was collected by the sensing region but which failed to propagate back in the clad fiber due to V-number mismatch. Earlier work has shown that tapering of the sensing region improves coupling of the fluorescence signal. While sensitivity was increased, there was a lack of reproducibility of signal magnitude from fiber to fiber. To produce a more consistent fiber probe which maintained sensitivity, signal return along the length of the probe was investigated. An effective design, termed a combination taper, was found which provided an even signal return along the fiber's length. The fiber tapers down to the V-number matching radius over 1 cm, maintaining total internal reflection, then continues to taper gently along the following 9 cm to near the distal end. The combination taper fiber provides not only the desired sensitivity, but also improved reproducibility.
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