An Indium(III)‐Catalyzed Synthesis of 4,4‐Dichloro‐1‐aryl‐N‐alkyl‐1‐yn‐3‐amines via an Intermolecular C(sp2)C(sp) Bond Formation

Abstract This paper demonstrates an indium(III) triflate‐catalyzed reaction of electron‐deficient α,α‐dichloroaldimines with terminal alkynes leading to a rapid and selective access to highly functionalized propargylic amines in good to excellent yields. The dichloromethylene moiety of the aldimine acts as an activating group to accomplish this transformation under very mild conditions.