Progress in diagnosis and treatment of hemolytic uremic syndrome

Hemolytic uremic syndrome (HUS) is a thrombotic microvascular disease, characterized by microvascular hemolytic anemia (red blood cell debris can be found), thrombocytopenia, and renal function damage. Micro thrombus mainly distributed in the kidney. Key factors for the pathogenesis includes infection, toxins, anti-endothelial cell antibodies, and drugs. In recent years, new recognition has been made for the causes and pathogenesis of HUS, and plasma infusion and plasmapheresis have been the most effective methods for treatment of HUS, greatly improving the survival rate of HUS patients. Key words: Hemolytic uremic syndrome; Child; Diagnosis; Treatment