Excimer laser in situ keratomileusis (LASIK) is the most recent evolution of the family of lamellar refractive surgery, which includes keratophakia, freeze myopic keratomileusis, epikeratoplasty, keratomileusis in situ, and Buratto-style excimer laser keratomileusis. LASIK is the marriage of the microkeratome, with its ability to resect a piano lamellar disc of corneal tissue, and the precision of the argon-fluoride excimer laser, operating at 193 nm to remove submicron layers of corneal stroma to achieve a highly predictable refractive result. Myopia, astigmatism, hyperopia, presbyopia, and complex ablations for abnormal topography have been attempted. Although LASIK as a technique is relatively young, the early results are very encouraging. Investigators worldwide are vigorously investigating its efficacy, predictability, stability, and safety.