Objective:Wild resources of gansu Bupleurum are exhausting,planting bupleurum and making it develop rapidly in all parts of gansu province,the saikosaponin ad contents of wild and home bupleurum are determined to ensure the quality of bupleurum that are used inclinic.Methods:The contents of saikosaponin ad were determined using high performance liquid chromatography.Results:The total contents of saikosaponin ad of gansu artificial bupleurum were 0.325 6%-0.725 1%,that were less than or close to wild bupleurum,and it contained higher saponin.Conclusion:The gansu artificial bupleurum can substitute the wild bupleurum.