Endoscope is a sophisticated medical equipment, now widely used in clinical examination and treatment. Endoscope can be divided into three kinds , namely soft endoscope, hard endoscope and capsule endoscope. In this paper, we process a investigation of the endoscope body, the host, the camera and the surgical instruments of soft endoscope and hard endoscope about clinical use of safety, including common misuse, cleaning and maintenance, sterilization and so on.