Objective: To observe the effect of Oseltamivir in treating early influenza.Methods: 144 patients with early influenza were randomly divided into two groups: the Oseltamivir group and Ribavirin group.Patients in the Oseltamivir group took Oseltamivir 75 mg orally twice daily for 2~5 days,while patients in the Ribavirin group reveived treatment of ribavirin for 3~7days.Results: There shows no obvious differences in patients between the two groups in the severity of the disease before the treatment,but there is of statistical difference in the fever release time of the influenza patients in both groups after the treatment(P0.05),the fever remission time in patients in the Oseltamivir group is shorter.Conclusion: Oseltamivir is a effective treatment for early influenza.