前药
化学
组合化学
计算机科学
方案(数学)
计算生物学
生物化学
生物
数学
数学分析
作者
Keren Haba,Mikhail Popkov,Marina Shamis,Richard A. Lerner,Carlos F. Barbas,Doron Shabat
标识
DOI:10.1002/anie.200461657
摘要
The knock-on effect of a single catalytic reaction by a specific enzyme on a prodrug platform initiates the sequential collapse of the whole array to release the active drug units (see scheme). Such a dendritic system may provide a means to improve selective chemotherapeutic approaches in cancer therapy. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2005/z461657_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
科研通智能强力驱动
Strongly Powered by AbleSci AI