Conversion of egg-shell to hydroxyapatite for highly sensitive detection of endocrine disruptor bisphenol A

As a typical endocrine disruptor, bisphenol A has caused many adverse effects to humans especially to babies. Egg-shell has been manipulated to build up hydroxyapatite under mild conditions. The resultant biomaterials have been successfully demonstrated to be highly sensitive to this pollutant, with a detection limit down to 0.246 nM.