Harnessing chitosan-adorned liposomes for enhanced drug delivery in cancer

药物输送 脂质体 壳聚糖 光热治疗 药品 医学 化疗 癌症 靶向给药 癌症治疗 药理学 癌症治疗 纳米技术 材料科学 化学 外科 内科学 生物化学
作者
Mohammad Arshad Javed Shaikh,Obaid Afzal,Waleed Hassan Almalki,Imran Kazmi,Sami I. Alzarea,Mohammed Jafar,Abdulmalik Saleh Alfawaz Altamimi,Vikash Jakhmola,Krishnan Anand,Sachin Kumar Singh,Kamal Dua,Gaurav Gupta
出处
期刊:Journal of Drug Delivery Science and Technology [Elsevier BV]
卷期号:85: 104619-104619 被引量:10
标识
DOI:10.1016/j.jddst.2023.104619
摘要

Cancer is a progressive disease that is caused by a combination of factors, including one's genetics, environment, and lifestyle choices. The pillars of cancer management include chemotherapy, surgical procedures, and radiation therapy; however, a wide variety of therapeutic combinations involving these and other therapies are also utilised. Despite its low success rate, chemotherapy remains the standard gold treatment. Drug carrier systems have been developed to address major challenges such as poor drug penetration and resistance. Future drug delivery systems should be based on chitosan liposomes because of their advantages, versatility, and ease of manufacture. In this article, we'll look at how liposomes based on chitosan can be used to treat several types of cancer through several different routes. Liposomes have been used in immunotherapy, and they can be engineered to respond to photothermal therapy as well as chemotherapeutic medicines and targeted agents.

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