909P A multi-cancer early detection model based on liquid biopsy of multi-omics biomarkers: A proof of concept study (PROMISE study)

Liquid biopsy is promising for cancer early detection to reduce mortality, particularly for those cancers without effective screening paradigms. The Pan-canceR early detectiOn by Multi-omIcS biomarkErs study (PROMISE, NCT04972201) is a prospective multicenter case-control study to assess the performance of the multi-cancer detection blood test (MCDBT) in the early detection of nine cancers in the lung, colorectum, liver, esophagus, pancreas, head and neck, ovary, and biliary tract.