溃疡性结肠炎
医学
炎症性肠病
疾病
临床试验
德尔菲法
重症监护医学
系统回顾
梅德林
内科学
计算机科学
人工智能
政治学
法学
作者
Ferdinando D’Amico,Fernando Magro,Britta Siegmund,Taku Kobayashi,Paulo Gustavo Kotze,Virginia Solitano,Bénédicte Caron,Sameer Al Awadhi,Ailsa Hart,Vipul Jairath,Axel Dignaß,Laurent Peyrin–Biroulet,Silvio Danese
出处
期刊:Inflammatory Bowel Diseases
[Oxford University Press]
日期:2023-08-07
被引量:3
摘要
Abstract The concept of disease clearance has been proposed as a potential target in ulcerative colitis (UC). We conducted a systematic review to investigate the role of disease clearance, defined as a composite outcome including simultaneous clinical, endoscopic, and histologic remission of disease in the management of patients with UC. Based on the literature data, statements regarding disease clearance were developed and voted on by the members of the International Organization for the Study of Inflammatory Bowel Diseases (IOIBD) according to a Delphi methodology. A definition of disease clearance was proposed to standardize its use in clinical practice and clinical trials and to provide practical recommendations for its implementation as a therapeutic target in UC.
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