心理学
心理神经免疫学
心理干预
社会心理的
焦虑
临床心理学
唤醒
心理弹性
认知
神经免疫学
心理治疗师
精神科
免疫系统
神经科学
医学
免疫学
中枢神经系统
作者
Julienne E. Bower,Kate R. Kuhlman
标识
DOI:10.1146/annurev-clinpsy-080621-045153
摘要
Research conducted over the past several decades has revolutionized our understanding of the role of the immune system in neural and psychological development and function across the life span. Our goal in this review is to introduce this dynamic area of research to a psychological audience and highlight its relevance for clinical psychology. We begin by introducing the basic physiology of immune-to-brain signaling and the neuroimmune network, focusing on inflammation. Drawing from preclinical and clinical research, we then examine effects of immune activation on key psychological domains, including positive and negative valence systems, social processes, cognition, and arousal (fatigue, sleep), as well as links with psychological disorders (depression, posttraumatic stress disorder, anxiety, schizophrenia). We also consider psychosocial stress as a critical modulator of neuroimmune activity and focus on early life adversity. Finally, we highlight psychosocial and mind–body interventions that influence the immune system and may promote neuroimmune resilience.
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