Research and Application of N-Ts Cyanamides in Organic Synthesis

N-Ts cyanamide, which has been widely used in the construction of nitrogen-containing framework, is one of the efficient and practical multifunctional synthetic precursors in organic synthesis.The progress in application of N-Ts cyanamide according to the reaction types is summarized, including the application in cyanation, cyclization reaction via cyanamide anion, cyanamidation, sulfonylation and cyclization reaction via cyano-group.The future development direction of this field is also prospected.