Oropharyngeal microbiome alterations in sarcopenia: a nested case-control study in older adults

Oropharyngeal microbial dysbiosis, characterized by lower diversity and a pro-inflammatory signature, is associated with sarcopenia. These findings highlight a potential relationship between the upper respiratory tract microbial environment and sarcopenia, a connection previously underappreciated. Understanding the interplay within the respiratory-gut-muscle axis may offer new perspectives on sarcopenia pathophysiology and its links with respiratory diseases.