医学
曲妥珠单抗
蒽环类
心脏毒性
内科学
乳腺癌
射血分数
肌钙蛋白
心脏病学
癌症
肿瘤科
心力衰竭
化疗
心肌梗塞
作者
Paaladinesh Thavendiranathan,Tamar Shalmon,Chun‐Po Steve Fan,Christian Houbois,Eitan Amir,Yobiga Thevakumaran,Emily Somerset,Julia M. Malowany,Camila Urzua-Fresno,Paul S. F. Yip,Chris McIntosh,Marshall S. Sussman,Christine Brezden‐Masley,Andrew T. Yan,Christine Koch,Neil Spiller,Husam Abdel‐Qadir,Coleen Power,Kate Hanneman,Bernd J. Wintersperger
出处
期刊：JAMA Cardiology
[American Medical Association]
日期：2023-04-12
卷期号：8 (6): 524-524
被引量：55
标识
DOI：10.1001/jamacardio.2023.0494
摘要
In women with ERBB2-positive breast cancer receiving sequential anthracycline and trastuzumab therapy, CMR tissue biomarkers suggest inflammation and edema peaking early during therapy and were associated with ventricular remodeling and BNP elevation. However, the increases in CMR biomarkers were transient, were not associated with LVEF or myocardial strain, and were not useful in identifying traditional CTRCD risk.
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