糖尿病足
医学
糖尿病溃疡
糖尿病足溃疡
糖尿病
内分泌学
作者
Priya Patel,Sanika Dongre,Alkeshkumar Patel,Grishma Patel
标识
DOI:10.1080/09205063.2024.2333068
摘要
The present research focuses on formulating and evaluating hydrogels modified with crosslinking agents using methylcellulose to treat diabetic foot ulcers (DFU). Methylcellulose hydrogels are prepared and characterized for their crosslinking capacity through FTIR and degradation studies. The optimized hydrogel is further assessed for viscosity, gel strength, contact angle, in-vitro biodegradation, water-vapor transmission rate, anti-bacterial activity, and in-vivo efficacy. The results demonstrate that the developed hydrogel exhibits promising properties for DFU treatment, including increased wound healing percentage, improved ulcer morphology, reduced levels of proinflammatory cytokines, and enhanced tissue characteristics. These findings suggest that the novel hydrogel composition could serve as a viable alternative to existing dressings for DFU management.
科研通智能强力驱动
Strongly Powered by AbleSci AI