滑膜肉瘤
粘液样脂肪肉瘤
脂肪肉瘤
医学
肉瘤
病理
癌症研究
标识
DOI:10.1016/s0140-6736(24)00411-2
摘要
Transgenic T-cell receptor-based immunotherapies hold the potential to revolutionise the treatment of cancer-testis antigen (CTA)-positive cancers. CTAs are exclusively found in immunologically privileged physiological, non-vitally essential adult testicular germ cells and can be massively overexpressed in cancers.1 One prominently used target for transgenic T-cell receptor-based immunotherapies is intracellular MAGE-A4, which is present in various solid cancers, including synovial sarcoma and myxoid round cell liposarcoma.
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