Decellularized scaffolds of porcine uterus reconstruct the endometrial microenvironment to promote uterine epithelial cell differentiation and organoid formation

vesicular-like structures, highlighting the scaffolds' advantage in enhancing cellular diversity. This study provides an advanced tool for elucidating endometrial microenvironment regulatory mechanisms and offers critical insights for improving organoid culture techniques and developing endometrial-specific synthetic scaffolds for its cultivation.