[Guangdong consensus on integrated Chinese and Western medicine management of prolonged disorders of consciousness].

", with abundant documentation in classical texts. Modern research has also explored the therapeutic effects and mechanisms of TCM for this condition and demonstrated its great potential in improving brain functional connectivity and promoting recovery of consciousness. However, the efficacy and mechanisms of TCM interventions still lack robust support from high-quality research evidence. Although integrated Chinese and Western medicine is widely employed for pDoC, no evidence-based guidelines or consensus specific to the condition are currently available. To improve the clinical proficiency across Guangdong Province and standardize the integrative management of pDoC, the consensus working group convened 35 leading Chinese and Western medicine experts in neurology, neurosurgery, and rehabilitation. Based on the latest domestic and international evidence, they developed recommendations on diagnosis, evaluation, integrated treatment strategies, complication management, healthcare system development, and ethical considerations, aiming to provide an authoritative reference for clinical decision-making in pDoC management.