医学
中性粒细胞弹性蛋白酶
蛋白酵素
痰
支气管扩张
弹性蛋白酶
丝氨酸
胃肠病学
蛋白酶抑制剂
炎症
免疫学
内科学
酶
化学
病理
生物化学
肺
肺结核
作者
James D. Chalmers,Charles Haworth,Mark L. Metersky,Michael R. Loebinger,Francesco Blasi,Oriol Sibila,Anne E. O’Donnell,Eugene J. Sullivan,Kevin C. Mange,Carlos Fernández‐Peña,Jun Zou,Charles L. Daley
标识
DOI:10.1056/nejmoa2021713
摘要
In this 24-week trial, reduction of neutrophil serine protease activity with brensocatib in patients with bronchiectasis was associated with improvements in bronchiectasis clinical outcomes. (Funded by Insmed; WILLOW ClinicalTrials.gov number, NCT03218917.).
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